Program

July 2 (Wed)
9:50‑10:00 Opening Remarks
Hiroyuki Aburatani (The University of Tokyo)
10:00-11:30 Session 1: Human Pangenome(Chair: Shinichi Morishita / Karen Miga)
10:00-10:30
- "From Complete Genomes to Pangenomes: Expanding Our Understanding of Human Haplotype Variation"
- Karen Miga (University of California, Santa Cruz)
10:30-11:00
- "Characterization of Somatic Structural Variation in Cancer Genomes Using Long Reads"
- Mikhail Kolmogorov (NCI)
11:00-11:30
- "Rare k-mers reveal centromere haplogroups underlying human diversity and cancer translocations"
- Yuichi Shiraishi (National Cancer Center Research Institute)
11:30-12:30
- Luncheon Seminar (1F: 101-103)
-
♦Oxford Nanopore Technologies K.K.
- ”Comprehensive understanding of the complex genomic and epigenomic characteristics of lung cancers through long-read whole-genome sequencing”
- Ayako Suzuki (The University of Tokyo)
- * This presentation will be presented in Japanese
- ”Latest Advances from Oxford Nanopore Technologies at London Calling 2025”
- Jihye Kim (Oxford Nanopore Technologies K.K.)
- Lunch & Poster Session (2F: Meeting Room)
- Meet the Expert (2F: 201-203)
12:30-13:30 Keynote Lecture (Chair: Tatsuhiro Shibata)
- "Somatic mutations in tumors and normal tissues"
- Núria López-Bigas (Institute for Research in Biomedicine, Barcelona / Pompeu Fabra University)
13:30-14:00
Coffee Break & Poster Session (2F: Meeting Room)
14:00-15:30 Technology Presentation (Moderato: Yuichi Shiraishi)
14:00-14:30
♦SCRUM Inc.
- ”大規模化するシングルセル解析”
- 相良 聡 (SCRUM Inc.)
14:30-15:00
♦TOMY DIGITAL BIOLOGY CO., LTD.
- ”Advancements in PacBio HiFi Sequencing: Enhancing Genomic Resolution and Accessibility”
- Khi Pin Chua (PacBio)
15:00-15:30
♦Biostream Co., Ltd.
- ”Defy Single Cell Gravity: escape platform constraints in single cell.”
- Chiara Reggio (Scale Biosciences)
15:30-17:30 Session 2: Large-scale Genome (Chair: Yukinori Okada)
15:30-16:00
- ”Biobank/cohort-scale human genetics and functional genomics”
- Wei Zhou (The Faculty of Medicine of Harvard University)
16:00-16:30
- "Striking Departures from Polygenic Architecture in the Tails of Complex Traits"
- Paul O'Reilly (Icahn School of Medicine)
16:30-17:00
- "Applying large scale human genetics data to target discovery: key questions and considerations"
- Melissa R. Miller (Pfizer Inc.)
17:00-17:30
- ”Gene–environment interactions underlying the dynamics of genetic architecture”
- Shinichi Namba (Graduate School of Medicine, The University of Tokyo)
17:30-18:30 Round Table : PRS (Moderator: Yukinori Okada / Hiroyuki Aburatani)
Wei Zhou (The Faculty of Medicine of Harvard University)
Paul O'Reilly (Icahn School of Medicine)
Melissa R. Miller (Pfizer Inc.)
Shinichi Namba (Graduate School of Medicine, The University of Tokyo)
July 3 (Thu)
9:30-11:30 Session 3: Digital pathology (Chair: Shumpei Ishikawa / Faisal Mahmood)
- "Foundation Models for Precision Health"
- Naoto Usuyama (Microsoft Research)
- "Multimodal, Generative, and Agentic AI for Pathology"
- Faisal Mahmood (Pathology, Harvard Medical School)
- "Quantitative Spatial Profiling of HistoPathology and Integrated Evaluation of Cancer Heterogeneity"
- Shumpei Ishikawa (The University of Tokyo / National Cancer Center Japan)
11:30-12:30
- Luncheon Seminar (1F: 101-103)
-
♦Illumina K.K.
- ”PIPseqの活用”
- Yutaka Suzuki (Graduate School of Frontier Sciences, the University of Tokyo)
- ”Illumina multi-omics product roadmap”
- Anthony Beckhouse (Illumina, inc.)
- Lunch & Poster Session (2F: Meeting Room)
- Meet the Editors Expert (2F: 201-203)
12:30-14:30 Technology Presentation (Moderator: Yutaka Suzuki)
12:30-13:00
♦Olink Proteomics K.K.
- * This session will be presented in Japanese
- ”The Power of the Proteome in Bridging Genetics and Disease: The Cutting Edge of PEA Technology”
- Wataru Kai (Proteomic Sciences, Thermo Fisher Scientific, Life Technologies Japan Ltd.)
13:00-13:30
♦Vizgen Inc.
- ”Extending Spatial Transcriptomics to Challenging Tissues: Enabling Discovery with MERFISH 2.0TM”
- George Emanuel (Vizgen Inc.)
13:30-14:00
♦Takara Bio Inc.
- ”Mapping Biology in Space: High-Resolution Spatial Multiomics with Seeker and Trekker”
- Christina Chang (Takara Bio USA)
14:00-14:30
♦MGI Tech Japan Co., Ltd.
- ”The Tool Advancement for Genomics, Cells and Organs: Integrated Innovation from Sequencing to Spatial Biology”
- Roy Tan (MGI APAC)
14:30-15:00
Coffee Break & Poster Session (2F: Meeting Room)
15:00-16:00 Plenary Talk (Chair: Hiroyuki Aburatani)
- "Somatic Evolution as a Lens into Human Biology and Disease"
- Dan Landau (Weill Cornell / New York Genome Center)
16:00-18:00 Session 4: Disease (Chair: Mamiko Sakata / Christian Steidl)
16:00-16:30
- "Dissecting the tumor microenvironment of B-cell lymphomas at single cell resolution"
- Christian Steidl (British Columbia Cancer Research Centre)
16:30-17:00
- "Genetic and Epigenetic Phylogenetic Reconstruction of Blood Cells in Ageing and Cancer"
- Jyoti Nangalia (Wellcome Sanger Institute / University of Cambridge)
17:00-17:30
- "Somatic Mosaicism in Brain Tumor Evolution"
- Jeong-Ho Lee (Korea Advanced Institute Science and Technology/Sovargen Co. LTD., )
17:30-18:00
- ”Single-cell and spatial omics to dissect the biology of heart failure”
- Seitaro Nomura (The University of Tokyo Hospital)
18:30-20:30 Banquet
July 4 (Fri)
9:30-11:30 Session 5: Multiomics in disease / New Frontiers in disese genomics (Chair: Yutaka Suzuki)
- "Understanding embryonic origins of tumours"
- Ankur Sharma (Garvan Institute of Medical Research)
- ”Tumor-infiltrating lymphocytes Acquire Tumor-Derived mtDNA Mutations via Mitochondrial Transfer: Implications for Cancer Immunotherapy Resistance”
- Yosuke Togashi (Okayama University / Okayama University Hospital)
- "Therapeutic Approaches Targeting mRNA Splicing and Stability in Cancer"
- Akihide Yoshimi (National Cancer Center Research Institute)
11:30-11:50 Poster Award
11:50-12:50
- Luncheon Seminar (1F: 101-103)
-
♦Twist Bioscience
- * This session will be presented in Japanese
- ”Genome analysis by a new library preparation method and clonal hematopoietic analysis by targeted sequencing”
- Akinori Kanai (Graduate School of Frontier Sciences, the University of Tokyo)
- ”Boosting Throughput and Reducing Cost in Genomic Sequencing with Twist FlexPrep™ UHT Workflow”
- Toshiki Taya (Twist Bioscience)
- Lunch & Poster Session (2F: Meeting Room)
- Meet the Expert (2F: 201-203)
12:50-14:50 Special Session (PAGS joint session):Technology Innovations and Beyond (Chair: Ken Kurokawa / Yutaka Suzuki)
- "Technology Innovations and Beyond"
- Yutaka Suzuki (Graduate School of Frontier Sciences, the University of Tokyo)
- "From Precise Microbiome Genomics to Precision Medicine"
- Ami Bhatt (Stanford University)
- "The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs"
- Jiwoon Park (Harvard Medical School / Weill Cornell Medicine)
- "Host Susceptibility to COVID-19 and COVID-19 Vaccination"
- Ho Namkoong (Keio University School of Medicine)
- "Editing the epigenome: multi-omics driven drug discovery & first-in-class therapy targeting histone methylation"
- Makoto Yamagishi (Graduate School of Frontier Sciences,The University of Tokyo)
14:50-16:50 Technology Presentation (Moderator: Akinori Kanai / Masahide Seki)
14:50-15:20
♦Roche Diagnostics K.K.
- ”Sequencing by Expansion (SBX), a versatile high-throughput single-molecule sequencing technology”
- Justin Nguyen (Roche Sequencing Solutions, Inc.)
15:20-15:50
♦Bruker Spatial Biology Inc.
- ”Multi-Omic subcellular imaging of the entire protein-coding transcriptome (same slide 19,000-plex RNA plus 76-plex protein): time to re-think how we do single-cell research of all types?”
- Joseph M Beechem (Bruker Spatial Biology. inc.)
15:50-16:20
♦10x Genomics
- * This session will be presented in Japanese
- ”See biology in new ways Access the full richness of biological complexity with single cell and spatial multiomics”
- Yuji Sato (10x Genomics)
16:20-16:50
♦BioTuring
- ”Omics and Spatial Analysis at the Speed of Life.”
- Bertrand Yeung (BioTuring)
16:20-17:50 Session 6: AI / Computatinal Biology (Chair: Nozomu Yachie)
16:20-16:50
- "Artificial intelligence inspired by genomics"
- Mile Sikic (Genome Institute of Singapore)
16:50-17:20
- "Synthetic and computational biology approaches to infer high-resolution mammalian developmental cell lineages"
- Nozomu Yachie (UBC Biomedical Engineering / The University of Osaka (PRIMe))
17:20-17:50
- "Biologically Informed Deep Generative Models Deciphering Systems Behind High Resolution Omics"
- Yasuhiro Kojima (National Cancer Center Research Institute)
17:50-18:00 Closing Remarks
Hiroyuki Aburatani (The University of Tokyo)
Exhibition
